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Sebastijan Ricko


Current position: Postdoc, Department of Chemistry, Aarhus University, Denmark

During his AIAS-COFUND Fellowship, Sebastijan Ricko worked on the project 'New Reaction Concepts in Organocatalysis'

Project at AIAS

Organocatalysis is the newest branch of asymmetric catalysis and allows for the formation of chiral molecules from simple substrates using small organic molecules as catalysts. While chemical reactions are driven by the conventional polar reactivity (nucleophile reacting with an electrophile), a major challenge in synthetic chemistry is the creation of a bond between two nucleophiles. A novel reaction concept was discovered recently, enabling the modification of the electronic character of one of the reacting nucleophiles, transforming it into an electrophilic species. This change in electronic character is based on an organocatalytic activation in combination with a redox-system. Thus, the purpose of the project will be to investigate the potential of this novel reaction concept and expanding it to a number of other new and fundamental reactions and methodologies. It is envisioned that this reaction concept can be extended to solve another challenge in chemical reactivity, e. g., the challenge of dual electrophilic coupling. If successful, these reaction concepts might open-up new avenues of important chemical reactivity by allowing currently impossible reactions to take place.

Project title:

New Reaction Concepts in Organocatalysis

Area of research:

Organic chemistry, organocatalysis

Fellowship period:

1 Aug 2020 - 31 Jul 2022

Fellowship type

AIAS-COFUND II Marie Skłodowska-Curie fellow

This fellowship has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 754513 and The Aarhus University Research Foundation.