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Markus Rinschen


Current position: Associate Professor, Department of Biomedicine, Aarhus University, Denmark and Medical Clinic, University Hospital Hamburg Eppendorf, Germany

During his AIAS-COFUND Fellowship, Markus Rinschen worked on the project 'Metabolic kidney protection'

Project description

The kidney is a central hub of mammalian metabolism, but its metabolic function is relatively understudied. Recent data shows that changes in kidney proximal tubule transport and metabolism, such as inhibition of sugar transport, is an effective therapeutic strategy in patients with diabetic and non-diabetic kidney disease. In this project, we aim understand the mechanism by which common amino acid-sugar conjugates alter or propagate kidney disease. We will analyze rodent models, cell cultures and human material using targeted and untargeted metabolomics as well as functional assays. The overarching goal is to explore the handling and molecular wiring of sugar-amino acid conjugates in the proteo-metabolomic space of the kidney in an interdisciplinary fashion. 

Project title: Metabolic kidney protection

Area of research: Health and Medical Sciences

Fellowship period: 1 Oct 2021 - 30 Dec 2023

Fellowship type: AIAS-COFUND II Marie Skłodowska-Curie fellow

This fellowship has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 754513 and The Aarhus University Research Foundation.