AIAS Seminar: Fulvio Mario Reggiori, AIAS Fellow
Cellular recycling: From cell digestion to coronaviruses
Info about event
AIAS Auditorium and online via Zoom
Speaker: Fulvio Mario Reggiori, AIAS Fellow
The seminar is held in-person, but online attendance is possible via:
The research of my team focuses on autophagy (from the Greek self-eating), a process that all the cells use to eliminate damage or what they do not need anymore. In addition to studying the mechanism of this process, we are also investigating the role of autophagy in immunity and neurodegeneration. A long time ago, in the context of autophagy and immunity, we became interested in coronaviruses and studied them for several years. Because of the SARS-CoV-2 outbreak, we went back to one of our findings since we believe that it could be exploited to develop a novel strategy to obtain compounds that could help to treat future coronavirus outbreaks. This is my AIAS project and after a brief introduction on autophagy, I will describe how we ended up studying coronavirus and which is the idea at the core of my AIAS project.
My research interests concern the degradative pathway of autophagy, and they focus on (1) The regulation and mechanism of autophagy, and (2) autophagy in disease (viral infections and neurodegeneration). We have generated unique electron microscopy procedures to integrate ultrastructural analyses into our investigations. This technology, plus our overall expertise in autophagy but also membrane traffic and organelle biogenesis, has permitted us to realize numerous collaborative studies to solve pressing biological questions.
What is an AIAS Seminar?
The AIAS Seminar is a session of seminars held by the AIAS fellow or by other speakers proposed by the fellows. In each seminar, one fellow will present and discuss his/her current research and research project, closing off with a question and discussion session.
All seminars are held in English.