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AIAS Fellows' Seminar: Asad Jan, AIAS Fellow

Protein aggregation in neurodegenerative diseases: Mechanisms of neuronal toxicity and opportunities for novel therapies

2018.05.22 | AIAS

Date Mon 03 Dec
Time 14:15 16:15
Location The AIAS Auditorium, Building 1632, Høegh-Guldbergs Gade 6B, 8000 Aarhus C


A large number of population, aged 65 years or over, is at risk of developing neurodegeneration due to Alzheimer (AD) and/or Parkinson disease (PD). During this seminar, I will provide a brief overview of the neuropathology of these two diseases, with particular emphasis on protein misfolding and aggregation in brain, and mechanisms of neuronal loss. I will also discuss some recent hypothesis, particularly the prion-like behaviour of misfolded proteins and dysregulation of mRNA translation, and their implications for novel therapies.

Short bio

I completed my graduate studies in 2005 with a professional degree in Clinical Medicine from Pakistan. Then, I pursued a PhD thesis in Neuroscience at EPFL in Switzerland which was awarded in 2010. I was a postdoctoral fellow at the department of Pathology, University of British Columbia in Canada during 2012-2017 before commencing my AIAS Marie-Curie COFUND fellowship in October 2017.

Asad Jan's project at AIAS

What is a Fellows' Seminar?

The AIAS Fellows' Seminar is a session of seminars held by the AIAS fellow or by other speakers proposed by the fellows. In each seminar, one fellow will present and discuss his/her current research and research project, closing off with a question and discussion session.

All seminars are held in English and open to the public. Registration to the seminar is not necessary.  Read more about the AIAS Fellows' Seminar here.

Lecture / talk