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AIAS Fellows' Seminar: Asad Jan, AIAS Fellow

Protein aggregation in neurodegenerative diseases: Mechanisms of neuronal toxicity and opportunities for novel therapies

Info about event

Time

Monday 3 December 2018,  at 14:15 - 16:15

Location

The AIAS Auditorium, Building 1632, Høegh-Guldbergs Gade 6B, 8000 Aarhus C

Contact

AIAS

Abstract

A large number of population, aged 65 years or over, is at risk of developing neurodegeneration due to Alzheimer (AD) and/or Parkinson disease (PD). During this seminar, I will provide a brief overview of the neuropathology of these two diseases, with particular emphasis on protein misfolding and aggregation in brain, and mechanisms of neuronal loss. I will also discuss some recent hypothesis, particularly the prion-like behaviour of misfolded proteins and dysregulation of mRNA translation, and their implications for novel therapies.

Short bio

I completed my graduate studies in 2005 with a professional degree in Clinical Medicine from Pakistan. Then, I pursued a PhD thesis in Neuroscience at EPFL in Switzerland which was awarded in 2010. I was a postdoctoral fellow at the department of Pathology, University of British Columbia in Canada during 2012-2017 before commencing my AIAS Marie-Curie COFUND fellowship in October 2017.

Asad Jan's project at AIAS

What is a Fellows' Seminar?

The AIAS Fellows' Seminar is a session of seminars held by the AIAS fellow or by other speakers proposed by the fellows. In each seminar, one fellow will present and discuss his/her current research and research project, closing off with a question and discussion session.

All seminars are held in English and open to the public. Registration to the seminar is not necessary.  Read more about the AIAS Fellows' Seminar here.