The research results published in ‘Nature Communications’ by Denton and co-authors has shown that a new treatment can affect a broad range of HIV virus variants.
AIAS Former Fellow Paul W. Denton has worked on the study during his fellowship period at AIAS. The results by Denton and the research group are published in the article ‘Broad activation of latent HIV-1 in vivo’ in Nature Communications this week.
Current HIV therapy controls the infection, but does not eradicate the virus from the body. In this study, the researchers analyzed over 4500 viral sequences isolated from participants in two clinical trials. The key finding was that viral RNA sequences detected following intervention were genetically diverse. This is an important positive outcome for incorporating such interventions into future HIV eradication strategies.
Read the study at: http://www.nature.com/articles/ncomms12731
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